A radical-mediated 1,3,4-trifunctionalization cascade of 1,3-enynes with sulfinates andtert-butyl nitrite: facile access to sulfonyl isoxazoles

An unprecedented indium-promoted three-component 1,3,4-trifunctionalization cascade of 1,3-enynes with sulfinates andtert-butyl nitrite for producing 5-sulfonylisoxazolesvia[3+2] annulation is reported.