Dentition defects damage the integrity of the dental arch, affecting smile esthetics and oral function. Compared to restorative treatment, pre-restoration orthodontic treatment overcomes the limitations of a single method, effectively avoiding excessive wear of natural teeth, reducing the number of units for restorative production to a certain extent, and potentially improving facial shape and occlusal relationship, which maximizes the therapeutic effect. This article explores the key points of pre-restoration orthodontic treatment for different types of dentition defects in terms of malocclusion manifestations, treatment objectives, treatment methods, and maintenance recommendations from the perspective of combined orthodontic restoration treatment.牙列缺损可破坏牙弓完整性,影响微笑美学效果和口腔功能。相较于单纯的修复治疗,修复前正畸治疗可弥补单一治疗方式的局限性,既可有效避免天然牙的过度磨除,一定程度上减少修复体制作单位,又可有效改善面型和咬合关系,以获得最大化的美学和修复治疗效果。本文从修复前正畸治疗角度,探讨不同类型牙列缺损的错(牙合)表现、矫治目标、矫治方法及保持等方面的要点,以供后续临床参考。.