区域选择性
位阻效应
苯胺
化学
组合化学
立体化学
有机化学
催化作用
作者
Philip W. Dyer,John Fawcett,Gerald A. Griffith,Martin J. Hanton,Céline Olivier,Adam R. Patterson,Samuel Suhard
摘要
Introduction of sterically demanding 1-isopropyl-2-methylpropyl or triisopropylsilyl groups at the nitrogen of aniline allows high-yielding regioselective para-substitution to be achieved using a lithiation/substitution sequence.
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