Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence

The peptide Boc-(Gly-Dpg-Gly)3-OBzl (I) has been synthesized to examine the conformational preferences of Dpg residues in a peptide sequence rich in glycine, which is known to be a poor helix promoter. The detailed NMR studies revealed that peptide (I) adopts a helical conformation in CDCl3. Keywords: Propyl Glycine, Glycine Rich Peptide