殖民地化
双歧杆菌
乳酸菌
生物
寄主(生物学)
微生物群
肠道菌群
共生
持久性(不连续性)
细菌
微生物学
遗传学
免疫学
工程类
岩土工程
作者
Yue Xiao,Qixiao Zhai,Hao Zhang,Wei Chen,Colin Hill
出处
期刊:Annual review of food science and technology
[Annual Reviews]
日期:2021-03-25
卷期号:12 (1): 213-233
被引量:42
标识
DOI:10.1146/annurev-food-061120-014739
摘要
Lactobacillus and Bifidobacterium spp. are best understood for their applications as probiotics, which are often transient, but as commensals it is probable that stable colonization in the gut is important for their beneficial roles. Recent research suggests that the establishment and persistence of strains of Lactobacillus and Bifidobacterium in the gut are species- and strain-specific and affected by natural history, genomic adaptability, and metabolic interactions of the bacteria and the microbiome and immune aspects of the host but also regulated by diet. This provides new perspectives on the underlying molecular mechanisms. With an emphasis on host-microbe interaction, this review outlines how the characteristics of individual Lactobacillus and Bifidobacterium bacteria, the host genotype and microbiome structure,diet, and host-microbe coadaptation during bacterial gut transition determine and influence the colonization process. The diet-tuned and personally tailored colonization can be achieved via a machine learning prediction model proposed here.
科研通智能强力驱动
Strongly Powered by AbleSci AI