苯胺
钯
化学
催化作用
芳基
氨基甲酸酯
苯胺类化合物
选择性
组合化学
立体化学
有机化学
烷基
作者
Nick Uhlig,Chao‐Jun Li
标识
DOI:10.1002/chem.201403712
摘要
Abstract The aniline carbamate is introduced as a new removable directing group for CH activation. Its versatility and ability as a directing group are demonstrated by its use in the ortho ‐arylation of a wide variety of aniline derivatives under palladium(II) catalysis, with symmetric diaryliodonium salts as aryl donors. The reaction differs from previously reported arylations in its selectivity and its mechanism, as elucidated by kinetic and isotopic experiments. The directing group can also be easily removed under a variety of conditions.
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