小型商用车
对映体药物
绝对构型
连接器
化学
对映选择合成
金属有机骨架
拓扑(电路)
纳米技术
组合化学
立体化学
催化作用
有机化学
材料科学
计算机科学
数学
操作系统
组合数学
吸附
作者
Haoze Wang,Xiaokun Pei,Davide M. Proserpio,Omar M. Yaghi
标识
DOI:10.1002/ijch.202100102
摘要
Abstract Metal‐organic frameworks (MOFs) with absolute structures are of particular interest as the asymmetry of their crystal structures enables wide applications from asymmetric catalysis to enantioselective separation. Previous reports on the synthetic strategies toward MOFs with absolute structures always required the use of chiral precursors or chiral templates, however, it is not always easy to obtain enantiopure starting materials. Here in, we report a new non‐centrosymmetric MOF, MOF‐829, synthesized from aluminium salt and achiral organic linker. Further comparisons are made between MOF‐829 and a reported Al‐based chiral MOF (MOF‐520) that is composed of the same metal ion and linker, and similarly synthesized without using chiral compounds. The configurations of the building units, the absolute structures of both MOFs, and their topologies were investigated in detail. We found that (i) topology is one of the determining factors in the formation of non‐centrosymmetric MOFs; (ii) the formation of chiral MOFs further requires the directionality of chiral linkers but more importantly chiral secondary building units (SBUs), which can be realized by fine tuning of the synthetic conditions. We envision that both synthetic exploration of chiral SBUs and the design of non‐centrosymmetric topologies will open a new direction in the design of MOFs with absolute structures.
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