Catalytic Asymmetric Allylation of 3‐Aryloxindoles by Merging Palladium Catalysis and Asymmetric H‐Bonding Catalysis

Abstract A catalytic asymmetric allylic alkylation reaction of 3‐aryloxindoles was accomplished via a dual catalysis merging palladium catalysis and asymmetric H‐bonding catalysis for the first time. Using this approach, allylated oxindoles bearing chiral all‐carbon quaternary centers were produced in high yields with good enantioselectivities (up to 92 % yield and 96:4 er ). magnified image