ChemInform Abstract: Synthesis of Podophyllotoxin and Related Analogues. Part 3. Synthesis of β‐Apopicropodophyllin Analogues with Modified Lactone Ring.

Abstract β‐Apopicropodophyllin (II), a dehydration product of the antitumor agent podophyllotoxin (I) with a manifold higher activity, serves as starting material for the synthesis of the analogues (IV), (VIII), (X) and (XI).