自溶(生物学)
真皮
液泡
海参
化学
组织蛋白酶
细胞外
细胞生物学
胶原酶
解剖
生物物理学
生物化学
生物
细胞质
酶
生态学
作者
Yuxin Liu,Dayong Zhou,Dongdong Ma,Yanfei Liu,Dongmei Li,Xiuping Dong,Mingqian Tan,Ming Du,Beiwei Zhu
标识
DOI:10.1016/j.foodchem.2016.05.173
摘要
The autolysis of sea cucumber (Stichopus japonicus) was induced by ultraviolet (UV) irradiation, and the changes of microstructures of collagenous tissues and distributions of cathepsin L were investigated using histological and histochemical techniques. Intact collagen fibers in fresh S. japonicus dermis were disaggregated into collagen fibrils after UV stimuli. Cathepsin L was identified inside the surface of vacuoles in the fresh S. japonicus dermis cells. After the UV stimuli, the membranes of vacuoles and cells were fused together, and cathepsin L was released from cells and diffused into tissues. The density of cathepsin L was positively correlated with the speed and degree of autolysis in different layers of body wall. Our results revealed that lysosomal cathepsin L was released from cells in response to UV stimuli, which contacts and degrades the extracellular substrates such as collagen fibers, and thus participates in the autolysis of S. japonicus.
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