生物结合
发光
光致发光
材料科学
牛血清白蛋白
纳米复合材料
铕
纳米颗粒
猝灭(荧光)
化学工程
碳二亚胺
荧光
纳米技术
高分子化学
化学
色谱法
光电子学
物理
量子力学
工程类
作者
Preeti Kukkar,Heena Sammi,Mohit Rawat,Pritpal Singh,Soumen Basu,Deepak Kukkar
出处
期刊:Nucleation and Atmospheric Aerosols
日期:2018-01-01
被引量:2
摘要
Luminescent metal organic frameworks (MOFs) have emerged as an exciting prospect for molecular sensing applications owing to their tunable porosity and optical properties. In this study, we have reported the synthesis of luminescent Europium-amino terephthalic acid (Eu-BDC-NH2) MOFs through solvothermal approach subsequently followed by their bioconjugation with anti-Bovine serum albumin (BSA) antibody using standard carbodiimide linkage chemistry. Subsequently nanocomposite of the bioconjugate and Zeolotic Imidazole Frameworks -8(ZIF-8) nanoparticles was prepared by adding varying volumes of ZIF-8 NPs to check the variation in photoluminescence (PL) intensity. Finally, optimized nanocomposites with increased PL intensity were treated with different concentrations of BSA to show a turn on effect on the PL intensity. The prepared nanocomposites were able to screen 0.1 ppm concentration of the BSA thus showing their high efficiency as a molecular sensor. This fluorescent platform would be further utilized for sensitive detection of pesticides in solution.
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