生物转化
真菌毒素
戒毒(替代医学)
玉米赤霉烯酮
展青霉素
化学
桔霉素
赭曲霉毒素
黄曲霉毒素
羟基化
葡萄糖醛酸化
生物化学
赭曲霉毒素A
酶
食品科学
微粒体
病理
替代医学
医学
作者
Peng Li,Ruixue Su,Ruya Yin,Daowan Lai,Mingan Wang,Yang Liu,Ligang Zhou
出处
期刊:Toxins
[MDPI AG]
日期:2020-02-14
卷期号:12 (2): 121-121
被引量:69
标识
DOI:10.3390/toxins12020121
摘要
Mycotoxins are toxic fungal secondary metabolites that pose a major threat to the safety of food and feed. Mycotoxins are usually converted into less toxic or non-toxic metabolites through biotransformation that are often made by living organisms as well as the isolated enzymes. The conversions mainly include hydroxylation, oxidation, hydrogenation, de-epoxidation, methylation, glycosylation and glucuronidation, esterification, hydrolysis, sulfation, demethylation and deamination. Biotransformations of some notorious mycotoxins such as alfatoxins, alternariol, citrinin, fomannoxin, ochratoxins, patulin, trichothecenes and zearalenone analogues are reviewed in detail. The recent development and applications of mycotoxins detoxification through biotransformation are also discussed.
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