The HIF-1α signaling pathway: A key approach to revealing the effects of Scutellaria baicalensis Georgi against lipopolysaccharide-induced spontaneous abortion

This study established a rigorous framework for screening and analyzing the therapeutic components of SBG and revealed that SBG is specifically effective against ESAs and maternal-fetal interface inflammation through the HIF-1α signaling pathway. These findings highlight SBG as a therapeutic agent for ESA and provide a foundation for future mechanistic studies.