粒体自噬
封面(代数)
纳米技术
心肌梗塞
医学
内科学
材料科学
化学
工程类
自噬
细胞凋亡
生物化学
机械工程
作者
Yang Jiao,Haimang Wang,Xiechuan Weng,Jihang Wang,Ying Li,Jian Shen,Weiwei Zhao,Qing Xi,Hongyu Zhang,Zhenhong Fu
出处
期刊:Aggregate
[Wiley]
日期:2024-10-01
卷期号:5 (5)
摘要
In this study, supramolecular self-assembled nanoparticles were developed with multi-functional properties of macrophage escape, cardiac targeting, and drug release for the treatment of myocardial infarction. The nanoparticles reduced cardiomyocyte apoptosis, alleviated myocardial interstitial fibrosis, and enhanced cardiac function based on the mechanism of the enhancement in mitophagy and alleviation in mitochondrial damage (e563).
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