Inhibition of Erythropoietic Stimulation by Testosterone in Polycythemic Mice Receiving Anti-Erythropoietin.

The injection of testosterone into polycythemic mice produces a small but significant stimulation of erythropoiesis, as measured by Fe59 uptake into the peripheral blood, if the interval between the injection of the hormone and Fe59 is 96 hours. This stimulation of erythropoiesis is completely abolished by the injection of immune serum against the hormone erythropoietin.