Discovery, Structural Optimization, and Mode of Action of Essramycin Alkaloid and Its Derivatives as Anti-Tobacco Mosaic Virus and Anti-Phytopathogenic Fungus Agents

displayed more than 50% inhibition rate against most of the 14 kinds of phytopathogenic fungi at 50 μg/mL. The current research lays a solid foundation for the application of essramycin alkaloids in crop protection.