喹啉
有害生物分析
病虫害综合治理
生物
毒理
生物技术
化学
农学
植物
有机化学
作者
Takaya Kobayashi,Hiroki Hotta,Takao Miyake,Masahiro Nomura,Ryo Horikoshi,Kazumi Yamamoto
出处
期刊:Journal of Pesticide Science
日期:2023-11-20
卷期号:48 (4): 168-174
标识
DOI:10.1584/jpestics.d23-035
摘要
Flometoquin, 2-ethyl-3,7-dimethyl-6-[4-(trifluoromethoxy)phenoxy]quinolin-4-yl methyl carbonate, is a novel insecticide with a structurally unique phenoxy-quinoline. It was discovered in 2004 by the collaborative research of Nippon Kayaku and Meiji Seika Kaisha, Ltd. (currently, Mitsui Chemicals Crop & Life Solutions, Inc.). The compound demonstrates strong and quick insecticidal action against a variety of thrips species at the nymphal and adult stages through contact and feeding activity, which could minimize crop damage and economic loss by insect pest species. In addition, flometoquin is safe for tested non-target arthropods, which makes it suitable for controlling the insect pests mentioned above under Integrated Pest Management (IPM) programs. Here, we describe a structure–activity relationship study from lead generation to the discovery of flometoquin and its insecticidal properties, including knockdown activity and effects against non-targeted arthropods.
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