[Treatment of periodontal disease, prevention and bisphosphonate].

The bisphosphonate has a high affinity in the hydroxyapatite which is the main constituent of the bone and remarkably suppresses the bone resorption. Thus bisphosphonate administer inhibits the resorption of the alveolar bone and the jaw bone with periodontitis, and there is a possibility of contributing to the treatment of the periodontitis. Then, the etidronate was prescribed for four patients periodontitis for 2-3 years according to the usual dose of the osteoporosis in addition to dental treatment, and the clinical course was followed. It is considered that etidronate controls the resorption of the alveolar bone for 2-3 years, maintains structure and function of the gums and the periodontal tissue, and is useful as the remedy of chronic periodontitis.