Thiyl-Radical-Catalyzed Photoreductive Hydrodifluoroacetamidation of Alkenes with Hantzsch Ester as a Multifunctional Reagent

Hydrodifluoroacetamidation of alkenes with readily available α-bromodifluoroacetamides was achieved by means of a photoreductive reaction catalyzed by the phenyl thiyl radical. A Hantzsch ester was used as the hydrogen donor and electron donor. This photoreductive pathway did not involve the oxidation of a carbon radical intermediate to a carbocation species.