脂类学
生物标志物发现
代谢组学
计算生物学
生物标志物
仿形(计算机编程)
疾病
人类健康
化学
蛋白质组学
生物信息学
医学
生物
计算机科学
色谱法
生物化学
病理
操作系统
基因
环境卫生
作者
Chunxiu Hu,Rob van der Heijden,Mei Wang,J. van der Greef,Thomas Hankemeier,Guowang Xu
标识
DOI:10.1016/j.jchromb.2009.01.038
摘要
Lipidomics is a lipid-targeted metabolomics approach aiming at comprehensive analysis of lipids in biological systems. Recently, lipid profiling, or so-called lipidomics research, has captured increased attention due to the well-recognized roles of lipids in numerous human diseases to which lipid-associated disorders contribute, such as diabetes, obesity, atherosclerosis and Alzheimer's disease. Investigating lipid biochemistry using a lipidomics approach will not only provide insights into the specific roles of lipid molecular species in health and disease, but will also assist in identifying potential biomarkers for establishing preventive or therapeutic approaches for human health. Recent technological advancements in mass spectrometry and rapid improvements in chromatographic techniques have led to the rapid expansion of the lipidomics research field. In this review, emphasis is given to the recent advances in lipidomics technologies and their applications in disease biomarker discovery.
科研通智能强力驱动
Strongly Powered by AbleSci AI