Recent Advances in DNA‐Templated Protein Patterning

Abstract In recent decades, the advancement of DNA nanotechnology enables precise nanoscale organization of diverse functional materials with DNA templates. Particularly, a variety of DNA‐templated protein patterns are constructed as powerful tools for programming biomimetic protein complexes. In this review, recent progress in DNA‐templated protein patterning, including cutting‐edge methods for arranging proteins with DNA templates, and protein patterns across varying dimensions are briefly summarized. Representative applications in biological analysis and biomedicine are discussed. DNA‐protein patterns with programmable dynamics, which hold promise in precision diagnosis and therapeutics are highlighted. Finally, current challenges and opportunities in the fabrication and application of DNA‐templated protein pattering are discussed.