[Objective] To explore the inhibitory effect of agrimol on K562 leukemia cell.[Method] Effects of agrimol on the cytoactive and apoptosis rate of K562 leukemia cell were respectively investigated through MTT experiment and flow cytometry.[Result] Agrimol(0.1,1,10 mg/ml) could dose-dependently inhibit the cytoactive of K562 leukemia cell,and improve significantly the apoptosis rate of K562 leukemiac cell(P0.05).[Conclusion] Agrimol had obvious inhibitory effects on K562 leukemia cell.