螺旋藻(膳食补充剂)
荟萃分析
血脂异常
医学
科克伦图书馆
随机对照试验
内科学
血脂谱
科学网
严格标准化平均差
梅德林
胃肠病学
胆固醇
疾病
生物
生物化学
原材料
生态学
作者
Iman Rahnama,Seyyed Mostafa Arabi,Mahla Chambari,Leila Sadat Bahrami,Vahid Hadi,Sayid Mahdi Mirghazanfari,Manfredi Rizzo,Saeid Hadi,Amirhossein Sahebkar
标识
DOI:10.1016/j.phrs.2023.106802
摘要
Cardiovascular diseases (CVD) are one of the most important causes of death worldwide. Dyslipidemia is one of the main causal risk factors for CVD that can be controlled by modifying lifestyle, which entails the use of healthy diets containing functional foods. The present study was conducted to summarize the effects of Spirulina on the lipid profile in previous randomized controlled trials.MEDLINE, Scopus, Clarivate Analytics Web of Science, and the Cochrane Library databases were searched systematically until January 2023, for clinical interventions that investigated the effect of Spirulina supplementation on plasma lipid profile concentrations.ooled results of 20 studies (with 23 arms and 1076 participants) indicated that Spirulina intervention significantly reduced LDL-C (SMD: -0.6, 95% CI: -0.9, -0.2, P<0.05), TC (SMD: -0.6, 95% CI: -0.9, -0.2, P<0.05) and TG (SMD: -0.6, 95% CI: -0.9, -0.2, P<0.05) levels while HDL-C levels were significantly increased (SMD: 0.3, 95% CI: 0.0, 0.6, P<0.05).The findings of the present meta-analysis and review show the usefulness of supplementing with Spirulina in improving serum levels of TC, TG, LDL-C, and HDL-C.
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