Current gaps in acute reperfusion therapies

PURPOSE OF REVIEW: Advances in intravenous thrombolysis and endovascular thrombectomy have significantly reduced disability and improved outcomes associated with acute ischemic stroke. RECENT FINDINGS: An expansion of indications for reperfusion therapies in select groups of patients to permit treatment in an extended time window, with large ischemic core, and with simplified imaging protocols have enabled a broader group of patients access to disability-sparing therapy. Cerebroprotection has had renewed development in the era of acute reperfusion. SUMMARY: In this review, we highlight recent developments in stroke reperfusion research and related questions that are under study or remain unanswered.