PP069 Fabrication, characterization, and evaluation of gallic acid-loaded polymeric nanoparticles dimethylbenz(a)anthracene (DMBA) induced mammary cancer in rodents via mTOR/Maf-1/PTEN signaling pathway

The present study focuses on the development and evaluation of gallic acid-loaded polymeric nanoparticles (GA-NPs) as a therapeutic strategy against dimethylbenz(a)anthracene (DMBA)-induced mammary cancer in rodents via its underlying mechansim. Gallic acid (GA), a potent natural antioxidant with anti-cancer properties, was encapsulated into polymeric nanoparticles to enhance its stability, bioavailability, and targeted delivery.