Blood stasis syndrome,which commonly exists in patients with malignant tumor,is not only a objective sign in cancer,but also plays an important role in the growth,invasion and metastasis of malignant tumor. Operation,radiotherapy and chemotherapy are the main treatments of cancer and all of these three treatments can reduce the tumor and relieve the symptoms.Therefore,operation,radiotherapy and chemotherapy can ease the patients' blood stasis state to a certain extent. However,operation,radiotherapy and chemotherapy may cause some damage to the body and can effect the stasis syndrome in the different time of treatment process. So,operation,radiotherapy and chemotherapy may have the potential promote to the invasion and metastasis of malignant tumor through effect the blood stasis state. Therefore,using blood-activating herbs in the different time of operation,radiotherapy and chemotherapy may have different effects on the tumor invasion and metastasis.