Objective:Inquire into the nervous system mechanism of that acupuncture could improve the learning and memory abilities of the patients of senile dementia. Method:Determined and compared the contents of monoarminergic neurotransmitter in the brain of senescence and adolescence rats. Result:The contents of monoarminergic neurotransmitter in brain of senescence rats were grossly reduced and acupuncture could increase the contents of monoarminergic neurotransmitter of senescence rats. Conclusion:To senescence rats, the contents of monoarminergic neurotransmitter were apparently reduced in senescence and acupuncture could reduce the descent of monoarminergic neurotransmitter in brain.