美罗华
环磷酰胺
医学
血管炎
抗中性粒细胞胞浆抗体
免疫学
养生
ANCA相关性血管炎
内科学
抗体
化疗
疾病
作者
John H. Stone,Peter A. Merkel,Robert Spiera,Philip Seo,Carol A. Langford,Gary S. Hoffman,Cees G. M. Kallenberg,E. William St. Clair,Anthony Turkiewicz,Nadia K. Tchao,Lisa Webber,Linna Ding,Lourdes P. Sejismundo,Kathleen Mieras,David Weitzenkamp,David Iklé,Vicki Seyfert‐Margolis,Mark Mueller,Paul Brunetta,Nancy B. Allen
标识
DOI：10.1056/nejmoa0909905
摘要
Cyclophosphamide and glucocorticoids have been the cornerstone of remission-induction therapy for severe antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis for 40 years. Uncontrolled studies suggest that rituximab is effective and may be safer than a cyclophosphamide-based regimen.
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