On the pathogenesis and clinical outcome of ANCA-associated vasculitis

<p>\n\n</p><table>\n <tbody><tr>\n <td>\n <p>Antineutrophil cytoplasmic antibody (ANCA)-associated\n vasculitis (AAV), including granulomatosis with polyangiitis (Wegener’s)\n (GPA) and microscopic polyangiitis (MPA), is a small-to-medium vessel\n vasculitis that affect multiple organs and is life-threatening when\n untreated. In this thesis, several aspects of ANCA-associated vasculitis\n concerning genetics, clinical and histopathological classification, treatment\n and long-term outcome were investigated.</p>\n </td>\n </tr>\n</tbody></table>