An update review on recent skin fillers

Facial rejuvenation has changed over the last decade, evolving from the rhytidectomy to an approach that focuses on revolumization, due to a more complete understanding of the changes to bone and soft tissue that occur with the aging face. Soft tissue augmentation using various injectable filler agents has gained popularity due to their nonsurgical, non-invasive procedures, instant cosmetic outcomes and limited recovery time. The skin filler market is booming and the variety of available skin fillers is increasing, providing the plastic surgeons many choices. Nonpermenant, biodegradable, resorbable agents may induce little complications, but they will normally disappear soon after injection. Semipermenant, biodegradable, biostimulary, nonresorbable fillers may induce a bit more complications, but they will normally disappear spontaneously in a few months. Permanent, nonresorbable fillers usually give rise to severe complications or reactions which may not disappear spontaneous. They may appear several years after the injection, and treatment is often insufficient. Unfortunately, the ideal filler with lasting effect but without any complication has not been discovered yet. In this review, we give an update on currently available skin filler agents, and what is new in recent 5 years.