突变体
拟南芥
表型
基因
生物
遗传学
拟南芥
点突变
突变
等位基因
分子生物学
作者
Hirotoshi Matsuo,Hiroko Fukushima,Shinpei Kurokawa,Eri Kawano,Takashi Okamoto,Hiroyasu Motose,Taku Takahashi
出处
期刊:FEBS Letters
[Wiley]
日期:2022-08-12
卷期号:596 (23): 3005-3014
标识
DOI:10.1002/1873-3468.14470
摘要
In Arabidopsis thaliana, the ACL5 gene encodes thermospermine synthase and its mutant, acl5, exhibits a dwarf phenotype with excessive xylem formation. Studies of suppressor mutants of acl5 reveal the involvement of thermospermine in enhancing mRNA translation of the SAC51 gene family. We show here that a mutant, sac59, which partially suppresses the acl5 phenotype, has a point mutation in JMJ22 encoding a D6-class Jumonji C protein (JMJD6). A T-DNA insertion allele, jmj22-2, also partially suppressed the acl5 phenotype while mutants of its closest two homologs JMJ21 and JMJ20 had no such effects, suggesting a unique role for JMJ22 in plant development. We found that mRNAs of the SAC51 family are more stabilized in acl5 jmj22-2 than in acl5.
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