Poly‐Catecholic Functionalization of Biomolecules for Rapid Gelation, Robust Injectable Bioadhesion, and Near‐Infrared Responsiveness (Adv. Healthcare Mater. 17/2023)

Bioadhesives In article 2203404 by Nasim Annabi, Ali Khademhosseini, and Paul S. Weiss and co-workers, an efficient chemical route for mussel-inspired functionalization of natural biomacromolecules is developed to enhance sutureless sealing of surgical wounds. Compared to standard catechol functionalization, poly(catechol) modification of gelatin biomacromolecules leads to injectable bioglues with rapid gelation for hemorrhage control, tough bioadhesion, and rapid infrared responsiveness.