The analog front end of a CCD imaging system is critical to the signal noise ratio of the camera.In order to increase the signal noise ratio of the imaging system,the layout and the PCB routing of the analog front end must be properly designed.Thus,based on analysis of the function of every part of the analog front end and design scheme of a specified CCD video signal processor,the power supply and grounding model of the specified CCD video signal processor with the analog and digital mixed signal device was established.And according to this model,the layout and PCB routing for the analog front end were analyzed and designed.The result shows that the signal noise ratio of the system could be up to 54 dB when the pixel clock is 6 MHz.