化学
甲醇
乙酰化
催化作用
乙酰氯
劈理(地质)
选择性
有机化学
氯化物
生物化学
断裂(地质)
基因
工程类
岩土工程
作者
Abu T. Khan,Ejabul Mondal
出处
期刊:Synlett
[Georg Thieme Verlag KG]
日期:2003-01-01
卷期号: (5): 0694-0698
被引量:52
摘要
A wide variety of tert-butyldimethylsilyl (TBS) ethers as well as tert-butyldiphenylsilyl (TBDPS) ethers 1 can be easily deprotected to the corresponding parent hydroxyl compounds 2 by employing catalytic amounts of acetyl chloride in dry MeOH at 0 °C to room temperature in good yields. Some of the major advantages are mild conditions, high efficiency, high selectivity, high yields, easy operation, and also compatibility with other protecting groups. Furthermore, no acetylation nor chlorination takes place under the experimental conditions.
科研通智能强力驱动
Strongly Powered by AbleSci AI