化学
脱羧
联轴节(管道)
氨基酸
可见光谱
偶联反应
组合化学
反应条件
有机化学
催化作用
光化学
光电子学
生物化学
机械工程
物理
工程类
作者
Yifan Li,Changhui Dai,Shentong Xie,Ping Liu,Peipei Sun
出处
期刊:Organic Letters
[American Chemical Society]
日期:2021-07-22
卷期号:23 (15): 5906-5910
被引量:18
标识
DOI:10.1021/acs.orglett.1c02014
摘要
An efficient visible-light-induced decarboxylative coupling reaction of N-protecting α-amino acids with heterocycles for the generation of aminoalkylated heterocycles is presented. A series of aminoalkylated heterocycles were obtained in moderate to good yields. Attractive features of this process include the generation of aminomethyl radical by an inexpensive organic photocatalyst under transition-metal-free conditions.
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