Glycan Profiling in Small Extracellular Vesicles with a SERS Microfluidic Biosensor Identifies Early Malignant Development in Lung Cancer (Adv. Sci. 33/2024)

Non‐Small Cell Lung Cancer In article number 2401818, Alain Wuethrich, Richard J. Lobb, Matt Trau, and co‐workers develop a surface‐enhanced Raman scattering (SERS) assay for detecting glycan signatures in extracellular vesicles (EVs) of early‐stage lung cancer patients. This cover artwork highlights the successful identification of glycans in tumor‐specific EVs via SERS barcodes under the stimulation of nanoscopic mixing. [Image: see text]