医学
胶质母细胞瘤
基因
CX3CR1型
小胶质细胞
癌症研究
肿瘤科
内科学
趋化因子
遗传学
炎症
生物
趋化因子受体
作者
Mathieu P. Rodero,Yannick Marie,Mathieu Coudert,Emmeline Blondet,Karima Mokhtari,Audrey Rousseau,William Raoul,Alain Carpentier,Florian Sennlaub,Philippe Déterre,Jean‐Yves Delattre,Patrice Debré,Marc Sanson,Christophe Combadière
标识
DOI：10.1200/jco.2008.17.2833
摘要
Few reliable prognostic molecular markers have been characterized for glioblastoma multiforme (GBM), considered the deadliest of human cancers. We hypothesized that genetic polymorphisms in chemokines and their receptors, which together control microglial cell mobilization, may influence survival.Distributions of one polymorphism of the chemokine CCL2 (-2518A
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