Actual issues in the pharmacological treatment of ADHD in adults with methylphenidate

Pharmacotherapy of attention-deficit/hyperactivity disorder in adulthood includes psychostimulants, antidepressants and atomoxetine, the first of them being considered the first choice. Methylphenidate efficacy has been demonstrated in adults when higher doses were used, in a proportionate similar way to what has been described in children. Methylphenidate profile of adverse events, including cardiovascular ones, seems to be safe. Key-words Attention deficit hyperactivity disorder, adults, treatment, psychostimulants, antidepressants, comorbidities.