A Comparative Study of Abana and Cholestyramine on Serum Lipids and Lipoproteins in Hypercholestrolaemic Rabbits

The comparative effects of Abana and cholestyramine on serum lipids and lipoproteins in hypercholesterolaemic rabbits were studied. Both the drugs, Abana and cholestyramine, reduced TC and LDL-c significantly less (p<0.05) in comparison to controls. The rise in TG was significantly less (p<0.01) in the Abana-treated group than in the cholestyramine and control groups. A significant reduction in the TC/HDL-c ratio was observed in the cholestyramine (p<0.01) and Abana (p<0.001) treated groups, whereas increased levels were observed in the control group.