检出限
荧光
双功能
没食子酸
化学
生物传感器
核化学
组合化学
光化学
色谱法
有机化学
抗氧化剂
生物化学
催化作用
物理
量子力学
作者
Junxue Liu,Wanhong Ma,Yufei Wang,Qinfen Gu,Qinhe Pan,Siyu Zong,Minghao Qin,Jiyang Li
出处
期刊:Food Chemistry
[Elsevier]
日期:2024-02-01
卷期号:433: 137241-137241
被引量:2
标识
DOI:10.1016/j.foodchem.2023.137241
摘要
Monitoring of gallic acid (GA) in food and biothiols in humans is crucial for body health. Nanozyme-mediated colorimetric strategy for evaluating them has been widely applied nowadays, however, the inferior efficient and susceptible single-signal recognition limit its further application. Herein, a sensitive biosensor was first constructed for bimodal detection of GA and biothiols based on CDs@MIL-53(Fe)-NO2, prepared through a facile and time-saving microwave treatment. Benefiting from the excellent fluorescent and electron transfer properties of CDs, CDs@MIL-53(Fe)-NO2 exhibited significant enhanced blue fluorescence and oxidase-like activity, which could oxide colorless 3,3',5,5'-tetramethylbenzidine without H2O2, and the blue product could quench the fluorescence of composite. The dual-mode assay based on such bifunctional nanozyme showed an extremely sensitivity towards GA/l-cysteine/homocysteine with the detection limit of 62/65/124 nM and 17/16/27 nM in colorimetric/fluorescent modes, respectively. The practicability in real samples and portability based on a smartphone of the analysis has been investigated with reliable results.
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