纳米技术
金属有机骨架
纳米医学
药物输送
癌症治疗
材料科学
纳米尺度
光动力疗法
纳米材料
癌症
医学
化学
纳米颗粒
有机化学
内科学
吸附
作者
Liangcan He,Yuan Liu,Joseph Lau,Wenpei Fan,Qunying Li,Chao Zhang,Pintong Huang,Xiaoyuan Chen
出处
期刊:Nanomedicine
日期:2019-05-01
卷期号:14 (10): 1343-1365
被引量:82
标识
DOI:10.2217/nnm-2018-0347
摘要
Nanoscale metal-organic frameworks (MOFs) have been widely used as controlled drug delivery vehicles and cancer therapy agents due to their intrinsic superior properties. Scientists have made remarkable achievements in the field of nanomedicine by using the MOFs and MOF-based multifunctional nanomaterials due to the easy synthesis into nanoscale and functionalization. In this review, we highlight the recent progress of nanoscale MOFs as drug delivery vehicles for cancer theranostics. We divide the discussion into three parts. The first and second parts focus on the drug delivery of unmodified MOF and modified MOFs, respectively, while the third part focuses on porphyrin MOFs as photosensitizers for photodynamic therapy. Finally, we conclude by identifying areas of research that we believe will propel the translation and application of MOFs.
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