化学
黄烷酮
催化作用
经络
氟化物
水溶液
迈克尔反应
铯
水介质
有机化学
组合化学
无机化学
柚皮素
类黄酮
抗氧化剂
作者
Motofumi Miura,Karin Shigematsu,Masaharu Toriyama,Shigeyasu Motohashi
标识
DOI:10.1016/j.tetlet.2021.153480
摘要
A total of 36 flavanones, which included polycyclic aromatic and heterocyclic rings, were readily synthesized via oxa -Michael addition from the corresponding hydroxychalcones with a catalytic amount of aqueous cesium fluoride solution under mild conditions. This method could be applied to the scalable synthesis of eriodictyol as a known potent inhibitor of the SARS-CoV-2 spike protein.
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