Dose fractionation of stereotactic body radiation therapy for locally advanced pancreatic cancer

Stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC) shows good signs of efficacy as measured by local control, which can also reduce toxicity. The dose fractionation in foreign countries have changed from conventional fractionation to single fraction and finally moderate hypofractionation. It is similar to that in China, with the dose fractionation changing from conventional fractionation to moderate hypofractionation. This review introduces the latest research results of dose fractionation of SBRT for LAPC. Key words: Pancreatic neoplasms/stereotactic body radiotherapy; Dose fractionation