自闭症谱系障碍
荟萃分析
自闭症
优势比
置信区间
联想(心理学)
心理学
子群分析
临床心理学
医学
精神科
心理治疗师
内科学
作者
Lei Wang,Weimin Shen,Hao Yao,Rongying Zheng,Wenshu Chen,Weixi Zhang
摘要
Autism spectrum disorder (ASD) and food allergy (FA) are global public health problems. Several studies have explored the association between ASD and FA, but the conclusions were inconsistent. The aim of this review was to evaluate the relationship between ASD and FA. The PubMed, Embase, and Web of Science databases were searched from inception to February 2, 2020. Studies investigating the association between ASD and FA were included. A random effects model was used to pool risk estimates. Subgroup analysis and sensitivity analysis were used to explore the potential sources of heterogeneity. Fifteen studies with a total of 293,130 participants were included in this review. The pooled prevalence of FA in individuals with ASD was 13% (95% confidence interval (CI): 0.10–0.17), while the pooled prevalence of FA in controls was 5% (95% CI: 0.04–0.07). The pooled odds ratio (OR) for FA in individuals with ASD was 2.45 (95% CI: 2.25–2.67). One study examined the prevalence of ASD in participants with FA. The prevalence of ASD in individuals with FA was 3.5% (95% CI: 0.029–0.042), while the prevalence of ASD in the control group was 1.6% (95% CI: 0.015–0.017). Five study examined the OR of ASD in participants with FA. The OR for ASD in individuals with FA was 1.95 (95% CI: 1.73–2.19). The results of this systematic review and meta‐analysis seem to reveal a significant association between ASD and FA. Lay Summary This systematic review and meta‐analysis evaluate the relationship between ASD and FA. We found that the prevalence of FA was higher in participants with ASD than in controls and participants with ASD were at risk of developing FA and the prevalence of ASD was higher in participants with FA than in controls and participants with FA were at risk of developing ASD. Additional research such as a prospective cohort study is required to better understand the relationship between ASD and FA.
科研通智能强力驱动
Strongly Powered by AbleSci AI